COSMETICS/PERSONAL CARE

Radiant Research is committed towards cruelty free testing for cosmetics and we have established in vitro cell based testing facility to provide non animal testing services. At Radiant Research, we maintain large cell repository with more than 60 different cell lines and optimized range of screening tests to offer End to End research services for various cosmetic and personal care products.

At Radiant Research, we have established three dimensional human skin equivalent models such as EpiDerm, EpiSkin, SkinEthic and Start-M to evaluate the efficacy, safety and permeation/absorption of cosmetic ingredients and cosmetics.

Preclinical

Efficacy studies In vitro

  • Skin Lightening
  • Sun Protection Factor (SPF)
  • Anti-aging
  • Skin tightening
  • Psoriasis
  • Scar/wound healing
  • Anti-acne
  • Anti-Dandruff
  • Deodorant
  • Skin Moisturizing
  • Skin pigmentation
  • Hair growth/anti-hair fall
  • Dermal permeation/absorption using EpiskinTM / EpidermTM/ Porcine skin/Start-M

Toxicology

  • 3T3 NRU phototoxicity (Skin irritation)
  • Acute Dermal toxicity
  • Acute ocular toxicity
  • Acute inhalation toxicity
  • Skin sensitization

Genotoxicity

  • AMES test (BRMT)
  • Chromosomal aberration in CHO-K1 cells

Clinical

  • Feasibility & Regulatory approvals.
  • Medical Writing
  • Project Management
  • Clinical trial and Site management
  • Clinical Trial Monitoring
  • Clinical Data Management
  • Biostatistics

Quality Control

Physico chemical analysis

  • Determination of pH
  • Melting point
  • Marker analysis by HPLC
  • Stability Studies (Real time & Accelerated Stability Studies)
  • Viscosity Measurements
  • Determination Ash Value
  • Refractive Index
  • Titrations

Microbial analysis

  • Total aerobic count
  • Specific Pathogen detection
  • Preservative efficacy testing (PET)
  • Water analysis
  • Time Kill Assay